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Keep track of Closely (three)pentobarbital will lower the level or effect of diazepam intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. Strong or average CYP3A4 inducers may possibly boost rate of diazepam elimination; thus, efficacy of diazepam could possibly be reduced.Observe Closely (one)pentobarb